DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Prss21

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_006245934.1	Gene:	Prss21 / 353251	RGDID:	727870	Length:	337	Species:	Rattus norvegicus

Alignment Length:	310	Identity:	87/310 - (28%)
Similarity:	140/310 - (45%)	Gaps:	63/310 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 QKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEY---PHMAAVGFESDRGQVDYK------- 173
            |..|.:|:.:.|....: .:||       :|:.|..:   |.....|.|::.|:..::
  Rat    23 QSTSSHVKPVDPEKPEL-QEAN-------LLSGPCGHRTIPSRIVGGEEAELGRWPWQGSLRVWG 79

  Fly   174 ---CGGSLISERFVLTAAHCTSIYEAPPKW-VRIGDLDLASEKRSVEAQLLR--IEQVFAHPNYK 232
               ||.:|::.|:|||||||......|..| |:.|:|.......:::|...|  ||.:|..|.|.
  Rat    80 NHLCGATLLNRRWVLTAAHCFQKDNDPFDWTVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKYT 144

  Fly   233 KKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFA-------MGYGA--TSFAKPMTNR 288
            :: :..|||||||...|..:.:::|:.|     |.:|..||       .|:||  ...:.|:.|.
  Rat   145 EQ-FPHDIALLKLSSPVTYSNFIQPICL-----LNSTYKFANRTDCWVTGWGAIGEDESLPLPNN 203

  Fly   289 LTNLNLTVVPNAECNAELPPLAETPS---GVLESQICAQDYILNRDTC---------QGDSGGPL 341
            |..:.:.::.|..||    .|.:.|.   .:....:||......:|.|         ||||||||
  Rat   204 LQEVQVAIINNTMCN----HLFKKPDFRINIWGDMVCAGSPEGGKDACFAKLTYAAPQGDSGGPL 264

  Fly   342 QLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIELTV 390
            ..|       ....::.:|:.|:|:.| |.:.|.|||.:|...:||.||:
  Rat   265 VCN-------QDTVWYQVGVVSWGIGCGRPNRPGVYTNISHHYNWIRLTM 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/278 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	77/277 (28%)
Prss21	XP_006245934.1	Tryp_SPc	57..303	CDD:214473	74/262 (28%)
Prss21	XP_006245934.1	Tryp_SPc	58..304	CDD:238113	75/262 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910