DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP009006

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_552907.3	Gene:	AgaP_AGAP009006 / 3291875	VectorBaseID:	AGAP009006	Length:	401	Species:	Anopheles gambiae

Alignment Length:	284	Identity:	82/284 - (28%)
Similarity:	136/284 - (47%)	Gaps:	53/284 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 CEQKYSEYVERIFPNDTAVAADANDADFDG-RVLARP---GEYPHMAAVGFESDRGQVDYKCGGS 177
            ||..|..:.::.             |||.| |..|:|   |.:||...:|::.::....:.|.|:
Mosquito   157 CETNYQRFRKKY-------------ADFVGDRGTAQPLEDGAHPHSVMIGWKVNKTATAWHCTGT 208

  Fly   178 LISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVE--AQLLRIEQVFAHPNYKKKMYYDDI 240
            ||:...|||.|.|.::       |.:|:.::|   |..:  ||::|:::...:|:|..|.:.:||
Mosquito   209 LINLNTVLTTAGCANM-------VSVGETNVA---RIYDGAAQIIRVKETIRYPSYNAKTHDNDI 263

  Fly   241 ALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAE 305
            |:||||.:|.:.|...|..||  .:|..|..:  |.......:.:|.|..|    ||.|.:|.
Mosquito   264 AVLKLESDVLVNENAIPACLW--RDLNRTPYY--GQEVHFDGQSLTARDKN----VVHNRDCQ-- 318

  Fly   306 LPPLAETPSGVLESQICAQDYILNRD-----TCQGDSGGPLQLNLPGRRRGHRIHY-HLIGITSY 364
               |..:.:.:...|:|.|::.|..|     .| |..|.|. :.|   :|.:.|:. :|:|:.||
Mosquito   319 ---LFTSHTELTNDQLCWQEFRLRPDGADAPNC-GRKGNPF-ITL---QRTNNIYLPYLVGLYSY 375

  Fly   365 GVFCRSSYPSVYTRVSSFLDWIEL 388
            ...|....|.|.||:||:::||.|
Mosquito   376 DRQCAGGEPIVATRISSYINWISL 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/252 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	73/251 (29%)
AgaP_AGAP009006	XP_552907.3	Tryp_SPc	<1..64	CDD:304450
		Tryp_SPc	184..398	CDD:304450	70/241 (29%)
		Tryp_SPc	184..397	CDD:214473	69/240 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910