DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP008996

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_552892.3	Gene:	AgaP_AGAP008996 / 3291870	VectorBaseID:	AGAP008996	Length:	249	Species:	Anopheles gambiae

Alignment Length:	229	Identity:	72/229 - (31%)
Similarity:	112/229 - (48%)	Gaps:	33/229 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 YKCGGSLISERFVLTAAHCTSIYEAPPK--WVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKK 234
            :|||.:|::|.:.:|||||  :...||.  .:|:|:.|||.|:.....|..|::.|.:||.:..:
Mosquito    34 HKCGAALLNENWAITAAHC--VDNVPPSDLLLRLGEYDLALEEEPYGYQERRVQIVASHPQFDPR 96

  Fly   235 MYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTI----AFAMGYGATSFAKPMTNRLTNLNLT 295
            .:..|:|||:..:.|.....:.||   ..||.....    ||..|:|......|:.:.|..:.:.
Mosquito    97 TFEYDLALLRFYEPVVFQPNIIPV---CVPENDENFIGRTAFVTGWGRLYEDGPLPSVLQEVTVP 158

  Fly   296 VVPNAECNAELPPLAET---PSGVLES----QICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHR 353
            |:.|..|        ||   .:|.:|.    .|||.......|:|:||||||:.:....:|
Mosquito   159 VIENNIC--------ETMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVIQRTDKR---- 211

  Fly   354 IHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
              :.|.|:.|:|:.| ..:.|.||||:|.|.|||
Mosquito   212 --FLLAGVISWGIGCAEPNQPGVYTRISEFRDWI 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/229 (31%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/227 (31%)
AgaP_AGAP008996	XP_552892.3	Tryp_SPc	6..243	CDD:214473	70/227 (31%)
AgaP_AGAP008996	XP_552892.3	Tryp_SPc	7..246	CDD:238113	72/229 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910