DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14642 and CLIPC1

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_552698.3	Gene:	CLIPC1 / 3291827	VectorBaseID:	AGAP008835	Length:	389	Species:	Anopheles gambiae

Alignment Length:	433	Identity:	128/433 - (29%)
Similarity:	194/433 - (44%)	Gaps:	106/433 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NLSVCLISF----------IGLWCLSNTHTQRLPPEGRMR------PLQDDSIRSP--------- 43
            ::::|:|.|          :|..|:    .||....|..|      |:.|| ||:.
Mosquito    10 SVALCVILFVIATVRCDLEVGDPCI----VQRTNEPGICRIVSECAPVIDD-IRNRRGNPTKCGF 69

  Fly    44 VDR--DIVFPELDAGPGKPEEKMWFHITDFQFDRVEGPTQPKPKPRQYPPPPMPGQPFPPPPGGF 106
            :||  .:..|::...|.                   ..|.|...||
Mosquito    70 IDRVQIVCCPQVGTTPA-------------------AATTPSTTPR------------------- 96

  Fly   107 KKKENKQRRLCEQKYSEYVERIFPNDTAVAADANDADF---------------DGRVLARPGEYP 156
                |:.:|:.| |.:||.:.:|..:...:..|::...               ||. ||:..|:|
Mosquito    97 ----NEHQRVAE-KCAEYGQAVFSKEYVNSLTASEPKLQTIDKCGHTAVELIVDGE-LAKAREFP 155

  Fly   157 HMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC-TSIYEAPPKWVRIGDLDLASEKRSVEAQLL 220
            |||.:|| .:..::.|.|||||:|:||:|||.|| ||....|...||:|:|.|||.......:..
Mosquito   156 HMALIGF-GEAPEIRYLCGGSLVSDRFILTAGHCLTSTNFGPATIVRLGELSLASSTDEAFPEDY 219

  Fly   221 RIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPM 285
            .|.:...||.||:..:|:||||:||.::|..:.|.||:.|.:...:|...|.|.|:||..|....
Mosquito   220 DIAERIPHPEYKQTSHYNDIALIKLNRKVIFSPYARPICLPLQAAIPQKRAIATGWGAIGFGLEQ 284

  Fly   286 TNRLTNLNLTVVPNAECNAELPPLAETPSGV-LESQICAQDYILNRDTCQGDSGGPLQL----NL 345
            ::.|..:.|.:....||..:..|..:..:|: ..:|:||......:||||||||||||:    |:
Mosquito   285 SSALLKVTLDMFRFEECKDQFEPTRKLRTGLNATTQLCAGSRNSTKDTCQGDSGGPLQVYNDANV 349

  Fly   346 PGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIE 387
                   ...|.:||:||:|..| .:..|:|||.|.|:|.|||
Mosquito   350 -------YCTYTIIGVTSFGQNCGLAGVPAVYTTVYSYLSWIE 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	95/247 (38%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	94/246 (38%)
CLIPC1	XP_552698.3	CLIP	39..79	CDD:197829	9/40 (23%)
		Tryp_SPc	143..386	CDD:238113	98/252 (39%)
		Tryp_SPc	143..384	CDD:214473	95/249 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910