DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP011909

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_320620.4	Gene:	AgaP_AGAP011909 / 3291449	VectorBaseID:	AGAP011909	Length:	400	Species:	Anopheles gambiae

Alignment Length:	246	Identity:	68/246 - (27%)
Similarity:	106/246 - (43%)	Gaps:	35/246 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQ 218
            |:|.|||:...|..|:..: ||.::|:....:|||||..........:.:|:.|:.:...|....
Mosquito   165 EFPMMAALVDGSKSGEGIF-CGATIITNYHAVTAAHCYMGRSIANLALLVGEHDITTGSESPYTA 228

  Fly   219 LLRIEQVFAHPNYKK--KMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAF--------- 272
            ||.:..:..|..|..  ....:|||:::...|:.....|.|..|        .|.|
Mosquito   229 LLLLASIKIHEGYSSTTSSSSNDIAIVRTRTEILFNAGVGPACL--------PIKFVGASFVGIQ 285

  Fly   273 --AMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQG 335
              |:|:|...:..|.:|....:.|.||..::|:|..|..:      .:.|:|.  ...|:||||.
Mosquito   286 LEAVGWGTLDYGAPKSNVPMKVALPVVNPSQCSALYPTFS------AQQQLCT--LTPNKDTCQS 342

  Fly   336 DSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSYPSVYTRVSSFLDWI 386
            ||||||.......:|.     :|:|...||:.|.:..|||.|.|..:..||
Mosquito   343 DSGGPLFYTDAYNKRA-----YLLGTIGYGIACATDRPSVSTNVLYYTQWI 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	68/246 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	66/244 (27%)
AgaP_AGAP011909	XP_320620.4	CUB	52..123	CDD:294042
		Tryp_SPc	154..388	CDD:214473	66/244 (27%)
		Tryp_SPc	155..391	CDD:238113	68/246 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910