DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and tmprss4b

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	222	Identity:	68/222 - (30%)
Similarity:	105/222 - (47%)	Gaps:	29/222 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 YKCGGSLISERFVLTAAHC-TSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKM 235
            :.|||||:|..::::|||| |...:...:|..:     ..:.:.::...:.::.:..|.:|.:..
Zfish   225 HMCGGSLLSTSWIISAAHCFTGRTQELSRWTVV-----LGQTKVMDVVGVSVDMIVIHKDYNRLT 284

  Fly   236 YYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAF-----AMGYGATSFAKPMTNRLTNLNLT 295
            ...|||:|||...|:..|.:.||.|   |  |..:|.     ..|:|.......:...|...::.
Zfish   285 NDFDIAMLKLTWPVKTGESILPVCL---P--PHQLAIKDMLVVTGWGLLKEGGALPTVLQKASVP 344

  Fly   296 VVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIG 360
            :|..:||:.  |.:..  |.:....:||.....|.|.||||||||| :.|..|       :.|||
Zfish   345 LVNRSECSK--PTIYS--SSITPRMLCAGFLQGNVDACQGDSGGPL-VYLSSR-------WQLIG 397

  Fly   361 ITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            |.|:||.| |...|.||..|:..||||
Zfish   398 IVSWGVGCAREGKPGVYADVTQLLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	68/222 (31%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	66/220 (30%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	66/220 (30%)
		Tryp_SPc	202..427	CDD:238113	68/222 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000