DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Tmprss6

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_006242057.1	Gene:	Tmprss6 / 315388	RGDID:	1307138	Length:	811	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	79/249 - (31%)
Similarity:	127/249 - (51%)	Gaps:	27/249 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC--TSIYEAPPKW-VRIGDLD 207
            |..::..||:|..|::..   ||:  :.|||:||::|:|:|||||  .....:|..| |.:|  .
  Rat   579 GGAMSSEGEWPWQASLQI---RGR--HICGGALIADRWVITAAHCFQEDSMASPRLWTVFLG--K 636

  Fly   208 LASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWV---FPELPTT 269
            :....|.......::.::|.||.:::..:..|:|||:|:..|..:..||||.|..   |.| |..
  Rat   637 MRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFE-PGQ 700

  Fly   270 IAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQ 334
            ..:..|:||.....|.::.|..:::.::|...|| |......||     ..:||......:|.||
  Rat   701 HCWITGWGAQREGGPGSSTLQKVDVQLIPQDLCN-EAYRYQVTP-----RMLCAGYRKGKKDACQ 759

  Fly   335 GDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIE 387
            |||||||....|..|      :.|.|:.|:|:.| |.::..|||||:..::||:
  Rat   760 GDSGGPLVCKEPSGR------WFLAGLVSWGLGCGRPNFFGVYTRVTRVVNWIQ 807

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/247 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	77/246 (31%)
Tmprss6	XP_006242057.1	SEA	88..185	CDD:279699
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:278486
		Tryp_SPc	576..806	CDD:214473	77/246 (31%)
		Tryp_SPc	577..809	CDD:238113	79/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910