DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Pamr1

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_038960854.1	Gene:	Pamr1 / 311252	RGDID:	1308745	Length:	814	Species:	Rattus norvegicus

Alignment Length:	446	Identity:	105/446 - (23%)
Similarity:	171/446 - (38%)	Gaps:	106/446 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LISFI--GLWCLSNTHTQRLPPEGR--------MRPLQDDSIRSPVDRDIVFPELDAGPGKPEEK 63
            ::||.  |.:.||....:.....|.        |:..::..|...|.|.::..::.:.. .|..:
  Rat   404 VVSFFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRE-TPLHQ 467

  Fly    64 MWFHITDFQFDRVEGPTQPKPKPRQYPPPPMPGQPFPP-PPG--------------GFKKKENKQ 113
            :  :.|.|...:::..:..|           |..||.. |||              .|..:....
  Rat   468 L--YSTAFSKQKLQDASTKK-----------PALPFGDLPPGYQHLHTQVQYECISPFYHRLGSS 519

  Fly   114 RRLCEQ--KYSEYVERIFPNDTAVAADANDADFDGRV--LARP----GEYPHMAAVGFESDRGQV 170
            ||.|.:  |:|.......|             ..|::  :|.|    ..:|..||: :....|..
  Rat   520 RRTCLRTGKWSGRAPSCIP-------------ICGKIESVASPKTQGTRWPWQAAI-YRRTSGVH 570

  Fly   171 D---YK------CGGSLISERFVLTAAHC-------TSIYEAPPKWVRIGDLDLASEKRSVEAQL 219
            |   :|      |.|:|::||.|:.||||       |.|..|..| |.:|......::.....|.
  Rat   571 DGGLHKGAWFLVCSGALVNERTVVVAAHCVTELGKVTIIKTADLK-VVLGKFYRDDDRDEKTIQN 634

  Fly   220 LRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWV-------FPELPTTIAFAMGYG 277
            |||..:..||||...:...|||:|||..:..::..|:|:.|..       |.|...|:|   |:.
  Rat   635 LRISAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSASFEESHITVA---GWN 696

  Fly   278 ATSFAKPMTNRLTNLN---LTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRD------TC 333
            ..:..:....:...|:   :.||.:..|..:..... .|..|.::..||     |:|      .|
  Rat   697 ILADVRSPGFKNDTLHYGMVKVVDSMLCEEQHEDHG-IPVSVTDNMFCA-----NKDPSTPSNIC 755

  Fly   334 QGDSGGPLQLNLPGRRRGHRIHYHLIGIT--SYGVFCRSSYPSVYTRVSSFLDWIE 387
            ..::||...|:.|||..... .:||:|:.  ||...|.:|..:.:|:|..|.||||
  Rat   756 TAETGGIAALSFPGRASSEP-RWHLVGLVSWSYDKTCSNSLSTAFTKVLPFKDWIE 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	76/280 (27%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	75/279 (27%)
Pamr1	XP_038960854.1	CUB	222..328	CDD:238001
		EGF_CA	333..366	CDD:238011
		CCP	374..436	CDD:153056	6/31 (19%)
		CCP	<502..537	CDD:153056	6/34 (18%)
		Tryp_SPc	555..812	CDD:238113	75/268 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910