DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	78/244 - (31%)
Similarity:	122/244 - (50%)	Gaps:	37/244 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKW-VRIGDLDLASEKRSVEA 217
            ::|...::.|     |..:.||||:|:..:::|||||......|..| |::|.:.|...  .|.:
  Rat   227 QWPWQVSLQF-----QGYHLCGGSVITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDS--PVPS 284

  Fly   218 QLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL----WVFPELPTTIAFAMGYGA 278
            .|  :|::..|..||.|...:||||:||.:.:...|.::|:.|    ..||:  ..:.:..|:||
  Rat   285 HL--VEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPD--GKLCWTSGWGA 345

  Fly   279 T----SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLE-SQICAQDYILNRDTCQGDSG 338
            |    ..|.|:.|...   :.::.|..||..     :...|::. |.:||.......|:||||||
  Rat   346 TEDGAGDASPVLNHAA---VPLISNKICNHR-----DVYGGIISPSMLCAGYLKGGVDSCQGDSG 402

  Fly   339 GPLQLNLPGRRRGHRIHYHLIGITSYGVFCRS-SYPSVYTRVSSFLDWI 386
            |||...       .|..:.|:|.||:|:.|.. :.|.||||::||||||
  Rat   403 GPLVCQ-------ERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/244 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	76/242 (31%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055
		Tryp_SPc	216..444	CDD:214473	76/242 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910