DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	74/266 - (27%)
Similarity:	113/266 - (42%)	Gaps:	64/266 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC-----TSIYEAPPKWVRIGD 205
            |..|....::|...::.|.:     .:.|||:||..::|||||||     ..|.|....:....:
  Rat   300 GGALTSESKWPWQVSLHFGT-----THICGGTLIDAQWVLTAAHCFFVTREKILEGWKVYAGTSN 359

  Fly   206 LDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL---------- 260
            |....|..|       |.|:..:.||..:....||||::|.|.:.|:.::.|..|
  Rat   360 LHQLPEAAS-------ISQIIINGNYTDEQDDYDIALVRLSKPLTLSAHIHPACLPLHGQTFGLN 417

  Fly   261 ---WVFPELPTTIAFAMGYGATSFAKPMTNR-LTNLNLTVVPNAECNAELPPLAETPSGVLES-- 319
               |:           .|:|.|......|:. |..:.:.::...:||..|         |.:|
  Rat   418 ETCWI-----------TGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYL---------VYDSYL 462

  Fly   320 ---QICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVS 380
               .:||.|....||:|||||||||......|       ::|.|:||:|..| :.:.|.|||:|:
  Rat   463 TPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNR-------WYLAGVTSWGTGCGQKNKPGVYTKVT 520

  Fly   381 SFLDWI 386
            ..|.||
  Rat   521 EVLPWI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/266 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	72/264 (27%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964
		SRCR_2	203..292	CDD:292133
		SRCR	216..288	CDD:278931
		Tryp_SPc	297..526	CDD:214473	72/264 (27%)
		Tryp_SPc	298..526	CDD:238113	72/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910