Protein Alignment CG14642 and GZMB

DIOPT Version :9

• Sequence 1: NP_001246901.1
• Gene: CG14642 / 40532
• FlyBaseID: FBgn0037222
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_004122.2
• Gene: GZMB / 3002
• HGNCID: 4709
• Length: 247
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 77/270 - (28%)
• Similarity: 130/270 - (48%)
• Gaps: 57/270 - (21%)

  Fly   137 ADANDADFDGRVL----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAP 197
            |||      |.::    |:|...|:||.:.....:..  .:|||.||.:.||||||||
Human    16 ADA------GEIIGGHEAKPHSRPYMAYLMIWDQKSL--KRCGGFLIRDDFVLTAAHC------- 65

  Fly   198 PKW-----VRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRP 257
              |     |.:|..::..::.:  .|.:.:::...||.|..|.:.:||.||:||::.:.|..|:|
Human    66 --WGSSINVTLGAHNIKEQEPT--QQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQP 126

  Fly   258 VRL-----WVFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVL 317
            :||     .|.|....::|   |:|.|:.....::.|..:.:||..:.:|.::|....::
Human   127 LRLPSNKAQVKPGQTCSVA---GWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDS----- 183

  Fly   318 ESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSS--YPSVYTRVS 380
            ..::|..|..:.:.:.:|||||||..|...:           ||.|||   |::  .|...|:||
Human   184 TIELCVGDPEIKKTSFKGDSGGPLVCNKVAQ-----------GIVSYG---RNNGMPPRACTKVS 234

  Fly   381 SFLDWIELTV 390
            ||:.||:.|:
Human   235 SFVHWIKKTM 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/256 (28%)
		Tryp_SPc	146..386	CDD:214473	71/255 (28%)
GZMB	NP_004122.2	Tryp_SPc	20..240	CDD:214473	70/254 (28%)
		Tryp_SPc	21..243	CDD:238113	72/256 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910