DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Habp2

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	85/257 - (33%)
Similarity:	129/257 - (50%)	Gaps:	47/257 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 GFESDRGQVDYK------------------CGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDL 208
            ||:|..|:..::                  ||||||...:||||||||.:.....| |.:||.||
  Rat   315 GFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIHPCWVLTAAHCTDMSTKHLK-VVLGDQDL 378

  Fly   209 ASEKRSVEAQLLRIEQVFAHPNYKKK--MYYDDIALLKLEK-----EVELTEYVRPVRLWVFPEL 266
              :|.....|..|:|::..:..|.::  :.::|||||||:.     .:| ::||:.|.|...|..
  Rat   379 --KKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALE-SKYVKTVCLPSDPFP 440

  Fly   267 PTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNR- 330
            ..|.....|:|.|...:. :.:|.:..:.::.||.||:.  .|.:  ..:.:|.|||.:  |.:
  Rat   441 SGTECHISGWGVTETGEG-SRQLLDAKVKLIANALCNSR--QLYD--HTIDDSMICAGN--LQKP 498

  Fly   331 --DTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSYPSVYTRVSSFLDWIELTV 390
              |||||||||||.....|.       |::.||.|:|..| ...|.|||:|:.||:||:.|:
  Rat   499 GSDTCQGDSGGPLTCEKDGT-------YYVYGIVSWGQEC-GKKPGVYTQVTKFLNWIKTTM 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	83/252 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	82/251 (33%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056
		Tryp_SPc	312..551	CDD:238113	84/254 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910