DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Tmprss7

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001099352.2	Gene:	Tmprss7 / 288118	RGDID:	1304655	Length:	829	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	77/306 - (25%)
Similarity:	124/306 - (40%)	Gaps:	75/306 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 LCEQKYSEYVERIFPNDTAVAADAND-ADFDGRVLARPGEYPHMAAVGFESDRGQVDYK------ 173
            :|.:|.:...:.|        .|..| :|.:|...:|...:.|....|.:|..|...::
  Rat   556 ICFRKQNAQCDGI--------VDCPDRSDEEGCGCSRSSPFLHRVVGGSDSQEGTWPWQVSLHFV 612

  Fly   174 ----CGGSLISERFVLTAAHC--TSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYK 232
                ||.|:||..::|:||||  .:....|..|.....:.:....:.|..    :.::..|..|.
  Rat   613 GSAHCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSP----VRRIVVHEYYN 673

  Fly   233 KKMYYDDIALLKLE---KEVELTEYVRPV-------------RLWVFPELPTTIAFAMGYG---- 277
            .:.:..|||||:|.   .|. |.:.::|:             :.||           .|:|
  Rat   674 SQTFDYDIALLQLSIAWPET-LRQLIQPICIPPVGQRVRSGEKCWV-----------TGWGRRHE 726

  Fly   278 ATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQ-ICAQDYILNRDTCQGDSGGPL 341
            |.|...|:   |....:.::....|        .:..|::.|: :||.......|.|:|||||||
  Rat   727 ADSKGSPI---LQQAEVELIDQTVC--------VSTYGIITSRMLCAGVMSGKSDACKGDSGGPL 780

  Fly   342 QLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            ..     ||.....:.|.||.|:|..| |.::|.||||||:|:.||
  Rat   781 SC-----RRKSDGKWILTGIVSWGYGCGRPNFPGVYTRVSNFVPWI 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/275 (26%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	69/273 (25%)
Tmprss7	NP_001099352.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..49
		SEA	94..190	CDD:279699
		CUB	<257..345	CDD:238001
		LDLa	470..504	CDD:238060
		LDLa	545..580	CDD:238060	6/31 (19%)
		Tryp_SPc	591..821	CDD:214473	66/261 (25%)
		Tryp_SPc	592..823	CDD:238113	68/262 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000