Protein Alignment CG14642 and TMPRSS12

DIOPT Version :9

• Sequence 1: NP_001246901.1
• Gene: CG14642 / 40532
• FlyBaseID: FBgn0037222
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 94/304 - (30%)
• Similarity: 142/304 - (46%)
• Gaps: 38/304 - (12%)

  Fly    98 PFPPPPGGFKKKENKQRRLCEQKYSEYVERIFPNDTAVAADANDADFD---------GRVLARPG 153
            |.|.|....::.|..::||..::          ...|.|.|...|...         |...|:.|
Human    33 PSPEPAASSQQAEAVRKRLRRRR----------EGGAHAEDCGTAPLKDVLQGSRIIGGTEAQAG 87

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVR-IGDLDLASEKRSVEA 217
            .:|.:.::..:..|..| :.|||:|:.||:||||||||.....|..|.. ||..::  ..|....
Human    88 AWPWVVSLQIKYGRVLV-HVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNI--HGRYPHT 149

  Fly   218 QLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL--WVFPELP-TTIAFAMGYGAT 279
            :.::|:.:..|||:..:.|.:||||..|:|.|...:|::|:.|  .||..|. .|..|..|:|.|
Human   150 KKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRT 214

  Fly   280 SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVL-ESQICAQDYILNRDTCQGDSGGPLQL 343
            ......||.|.:..:..:....||:|     .:..|:: .:..||.|.....|||:|||||||..
Human   215 KEEGNATNILQDAEVHYISREMCNSE-----RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMC 274

  Fly   344 NLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            .||..:|     :.::||||||..| |..:|.||...|.:..|:
Human   275 YLPEYKR-----FFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	84/247 (34%)
		Tryp_SPc	146..386	CDD:214473	83/245 (34%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..63		8/39 (21%)
		Tryp_SPc	78..316	CDD:238113	84/249 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910