DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and f10

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	373	Identity:	96/373 - (25%)
Similarity:	152/373 - (40%)	Gaps:	66/373 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LPPEGRMRPLQDDSIRSPVDRDIVFPELDAGPGKPEEKMWFHITDFQFDRVEGPTQPKP--KPRQ 88
            |.|.|:....||     |....:::|       |....::||..:......|..|:.:.  :|..
Zfish   154 LAPNGKSCQSQD-----PFKCGVIYP-------KKTRSIFFHTPNITESENEEETELEATIEPVY 206

  Fly    89 YPPPPMPGQPFPPPPGGFKKKENKQRRLCEQKYSEYVERIFPNDTAVAADANDADFDGRVLARPG 153
            ....|:..|            .:....|.|.:..| .|.|.|    |.:.|.|......|...||
Zfish   207 NHSNPLNNQ------------TDSMFGLHELEIIE-EEPILP----VVSTAGDGRIVNGVECPPG 254

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLD-LASEKRSVEA 217
            :.|..|.:..|::.|    .|||::::|.|:|:||||.:  |:....|.:|:.| |..|.|....
Zfish   255 DCPWQALLINENNMG----FCGGTILTEHFILSAAHCMN--ESLSIRVVVGEYDTLVPEGREATH 313

  Fly   218 QLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAM-------- 274
            .   ::::..|.||:...|::||||:||.|.::.|:|:.|..|   ||:.......|
Zfish   314 D---VDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACL---PEMKFAERVLMQQDDGLVS 372

  Fly   275 GYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGG 339
            |:|........:..|..|.:..|..|:|      :..:...:.....||......:|.|||||||
Zfish   373 GFGRVREGGLSSTILQKLTVPYVNRAKC------IESSNFKISGRMFCAGYDQEEKDACQGDSGG 431

  Fly   340 PLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            |........       :.:.|:.|:|..| |.....|||:||.::.||
Zfish   432 PHVTRFKNT-------WFITGVVSWGEGCARKGKYGVYTQVSKYIMWI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/251 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/249 (28%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342	3/6 (50%)
		Tryp_SPc	244..472	CDD:214473	70/252 (28%)
		Tryp_SPc	245..474	CDD:238113	72/253 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910