DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and F9

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_113728.1	Gene:	F9 / 24946	RGDID:	2589	Length:	462	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	80/276 - (28%)
Similarity:	126/276 - (45%)	Gaps:	46/276 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 IFPNDTAVAADANDADFDGRVL----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAA 188
            |..|.|..:...||..   ||:    |:||:.|....:     .|:::..|||::|:|::::|||
  Rat   211 ILDNLTENSEPINDFT---RVVGGENAKPGQIPWQVIL-----NGEIEAFCGGAIINEKWIVTAA 267

  Fly   189 HCTSIYEAPPKWVRI--GDLDLASEKRSVEAQLLRIEQVFAHPNYKKKM--YYDDIALLKLEKEV 249
            ||..    |...:.:  |:.:: .||...| |...:.:...|..|...:  |..|||||:|:|.:
  Rat   268 HCLK----PGDKIEVVAGEHNI-DEKEDTE-QRRNVIRTIPHHQYNATINKYSHDIALLELDKPL 326

  Fly   250 ELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPMTNR------LTNLNLTVVPNAECNAELPP 308
            .|..||.|:  .|..:..|.|....|.|..|....:.|:      |..|.:.:|..|.|
  Rat   327 ILNSYVTPI--CVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATC------ 383

  Fly   309 LAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC--RSS 371
            |..|...:..:..||......:|:|:||||||....:.|..       .|.||.|:|..|  :..
  Rat   384 LRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTS-------FLTGIISWGEECAMKGK 441

  Fly   372 YPSVYTRVSSFLDWIE 387
            | .:||:||.:::||:
  Rat   442 Y-GIYTKVSRYVNWIK 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/256 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	73/255 (29%)
F9	NP_113728.1	GLA	21..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	127..163	CDD:291342
		Tryp_SPc	227..455	CDD:214473	73/254 (29%)
		Tryp_SPc	228..458	CDD:238113	74/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910