DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CG30187

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	73/240 - (30%)
Similarity:	115/240 - (47%)	Gaps:	32/240 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 MAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRI 222
            ||||     ..:..:.|||:||.:|||||||||....:       :..:.|.:..:|..|....:
  Fly    50 MAAV-----HNRTHFICGGTLIHKRFVLTAAHCIVDQD-------VQSVSLGAYNKSDPADRKDV 102

  Fly   223 EQVFAHPNYK-KKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPMT 286
            .....|.::. :..|.:||.||||..:|.....:||:.:.:...:...:.....:.|..:.....
  Fly   103 ITAVVHSSFDVRASYENDIGLLKLSSDVIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRG 167

  Fly   287 NRLTNLNLTVVPN----AECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPG 347
            |:.:::..|::.|    .||..|   |:..||   |.||||.  :.:.|||.|||||||..::..
  Fly   168 NKTSDILQTIILNHLDREECYME---LSVYPS---EKQICAG--VPSGDTCGGDSGGPLTNDVFI 224

  Fly   348 RRRGHR-IHYHLIGITSYG-VFCRSSYPSVYTRVSSFLDWIELTV 390
            :..|:| :.:   ||.|.| ..|...  .|||.:.||.|||::|:
  Fly   225 QGIGNREVQF---GIISVGKTSCDGQ--GVYTDLMSFADWIKMTI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/235 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/234 (30%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	70/234 (30%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910