DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Ovch2

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_766496.2	Gene:	Ovch2 / 244199	MGIID:	3045251	Length:	609	Species:	Mus musculus

Alignment Length:	400	Identity:	102/400 - (25%)
Similarity:	153/400 - (38%)	Gaps:	135/400 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LISFIGLWCLSNTHTQRLPPEGRMRPLQDDSIRSPVDRDIVFPELDAGPG--KPEEKMWFHITDF 71
            ||..:|:.||...|::.|           .|||:|          |.|..  ||:.:.:|.:
Mouse     8 LILILGMVCLEQGHSETL-----------SSIRNP----------DCGQSLVKPQPQNYFSL--- 48

  Fly    72 QFDRVEGPTQPKPKPRQYPPPPMPGQPFPPPPGGFKKKENKQRRLCEQKYSEYVERIFPNDTAVA 136
             |.|:.|.:|                                           ||:
Mouse    49 -FSRIVGGSQ-------------------------------------------VEK--------- 60

  Fly   137 ADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYE-APPKW 200
                            |.||...::     :.:..:.|||::||.::|:|||||.:... |....
Mouse    61 ----------------GSYPWQVSL-----KQKQKHICGGTIISSQWVITAAHCMANRNIALTLN 104

  Fly   201 VRIGDLDLASEKRSVEAQLLRIEQVFAHPNY--KKKMYYDDIALLKLEKEVELTEYVRPVRLWVF 263
            |..|:.||:..:..  .|.|.||.:..||.:  :|.|.| ||||||:....:..::||||.|
Mouse   105 VTAGEHDLSQAEPG--EQTLAIETIIIHPQFSTRKPMIY-DIALLKMAGTFQFGQFVRPVCL--- 163

  Fly   264 PELPTT------IAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQIC 322
            || |..      |....|:|..|....:...|..:||.::...||.|.|..|....:|  ::.:|
Mouse   164 PE-PGEHFNAGFICTTAGWGRLSEGGRLPQVLQQVNLPILTQEECEAVLLTLKNPITG--KTFLC 225

  Fly   323 AQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSY-----------PSVY 376
            .......||.|||||||.|...   .|:|   .:.|.|:||:|:.|..|:           |.::
Mouse   226 TGSPDGGRDACQGDSGGSLMCQ---NRKG---AWTLAGVTSWGLGCGRSWRNNARKKEQGSPGIF 284

  Fly   377 TRVSSFLDWI 386
            |.:...|.||
Mouse   285 TDLRRVLPWI 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	79/260 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	78/259 (30%)
Ovch2	NP_766496.2	Tryp_SPc	51..294	CDD:214473	83/330 (25%)
		Tryp_SPc	52..297	CDD:238113	83/330 (25%)
		CUB	317..420	CDD:238001
		CUB	431..542	CDD:238001
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	580..609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910