DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	250	Identity:	80/250 - (32%)
Similarity:	122/250 - (48%)	Gaps:	36/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKW-VRIGDLDLA 209
            |.|.|....:|...::.:..     .:.||||::...::||||||...|.....| ||.|...|.
Mouse   205 GGVEAPVDSWPWQVSIQYNK-----QHVCGGSILDPHWILTAAHCFRKYLDVSSWKVRAGSNILG 264

  Fly   210 SEKRSVEAQLLRIEQVF-AHPN--YKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPE--LPTT 269
            :      :..|.:.::| |.||  |.|:   .||||:||:..:..:..|||:.|....|  :|.|
Mouse   265 N------SPSLPVAKIFIAEPNPLYPKE---KDIALVKLQMPLTFSGSVRPICLPFSDEVLVPAT 320

  Fly   270 IAFAMGYGAT-SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSG-VLESQICAQDYILNRDT 332
            ..:.:|:|.| .....|::.|...::.|:.:..||||     :...| |....:||......:||
Mouse   321 PVWVIGWGFTEENGGKMSDMLLQASVQVIDSTRCNAE-----DAYEGEVTAEMLCAGTPQGGKDT 380

  Fly   333 CQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRS-SYPSVYTRVSSFLDWI 386
            |||||||||..        |...:.::||.|:|..|.. |.|.|||:|:::|:||
Mouse   381 CQGDSGGPLMY--------HSDKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	79/249 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	78/248 (31%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335
		Tryp_SPc	202..427	CDD:214473	78/248 (31%)
		Tryp_SPc	203..430	CDD:238113	79/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910