DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and F9

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_032005.1	Gene:	F9 / 14071	MGIID:	88384	Length:	471	Species:	Mus musculus

Alignment Length:	322	Identity:	86/322 - (26%)
Similarity:	137/322 - (42%)	Gaps:	57/322 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 PGQPFPPPPGGFKKKENKQRR----LCEQKYSEYVERIFPNDT----AVAADANDA-----DFDG 146
            |..|||...........|..|    .....|....|.:|..|.    |:..:..::     ||.
Mouse   172 PTVPFPCGRASISYSSKKITRAETVFSNMDYENSTEAVFIQDDITDGAILNNVTESSESLNDFT- 235

  Fly   147 RVL----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRI--GD 205
            ||:    |:||:.|....:     .|:::..|||::|:|::::|||||..    |...:.:  |:
Mouse   236 RVVGGENAKPGQIPWQVIL-----NGEIEAFCGGAIINEKWIVTAAHCLK----PGDKIEVVAGE 291

  Fly   206 LDLASEKRSVEAQLLRIEQVFAHPNYKKKM--YYDDIALLKLEKEVELTEYVRPVRLWVFPELPT 268
            .::  :|:....|...:.:...|..|...:  |..|||||:|:|.:.|..||.|:  .|.....|
Mouse   292 YNI--DKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPI--CVANREYT 352

  Fly   269 TIAFAMGYGATSFAKPMTNR------LTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYI 327
            .|....|.|..|....:.|:      |..|.:.:|..|.|      |..|...:..:..||....
Mouse   353 NIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATC------LRSTTFTIYNNMFCAGYRE 411

  Fly   328 LNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC--RSSYPSVYTRVSSFLDWIE 387
            ..:|:|:||||||....:.|..       .|.||.|:|..|  :..| .:||:||.:::||:
Mouse   412 GGKDSCEGDSGGPHVTEVEGTS-------FLTGIISWGEECAMKGKY-GIYTKVSRYVNWIK 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/256 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	71/255 (28%)
F9	NP_032005.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:291342
		Tryp_SPc	236..464	CDD:214473	71/254 (28%)
		Tryp_SPc	237..467	CDD:238113	72/256 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910