DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and F10

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001229297.1	Gene:	F10 / 14058	MGIID:	103107	Length:	493	Species:	Mus musculus

Alignment Length:	275	Identity:	77/275 - (28%)
Similarity:	123/275 - (44%)	Gaps:	28/275 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 VERIFPNDTAVAADAND-ADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAA 188
            :|.:..|:|.....::| ....|....:.||.|..|.:..|.:.|    .|||::::|.::||||
Mouse   224 IELLNLNETQPERSSDDLVRIVGGRECKDGECPWQALLINEDNEG----FCGGTILNEFYILTAA 284

  Fly   189 HCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTE 253
            ||  :::|....||:||.:  :||......:..::.|..|..:::..|..|||:|:|:..:....
Mouse   285 HC--LHQARRFKVRVGDRN--TEKEEGNEMVHEVDVVIKHNKFQRDTYDYDIAVLRLKTPITFRM 345

  Fly   254 YVRPVRL----WVFPELPT-TIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETP 313
            .|.|..|    |....|.| ......|:|.|......:|.|..|.:..|....|.      ..|.
Mouse   346 NVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCK------LSTS 404

  Fly   314 SGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYT 377
            ..:.::..||.......|.||||||||........       |::.||.|:|..| |.....:||
Mouse   405 FSITQNMFCAGYEAKLEDACQGDSGGPHVTRFKNT-------YYVTGIVSWGEGCARKGKYGIYT 462

  Fly   378 RVSSFLDWIELTVWA 392
            :|::||.||:.::.|
Mouse   463 KVTTFLKWIDRSMKA 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/246 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/245 (29%)
F10	NP_001229297.1	GLA	36..97	CDD:214503
		EGF_CA	98..134	CDD:238011
		FXa_inhibition	141..176	CDD:291342
		Tryp_SPc	243..471	CDD:214473	70/248 (28%)
		Tryp_SPc	244..473	CDD:238113	72/249 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910