DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP011719

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_320793.4	Gene:	AgaP_AGAP011719 / 1280920	VectorBaseID:	AGAP011719	Length:	762	Species:	Anopheles gambiae

Alignment Length:	277	Identity:	101/277 - (36%)
Similarity:	143/277 - (51%)	Gaps:	28/277 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 CEQKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISE 181
            ||.:   |...::| |..:::.:.         |.|||:.|:||:|:....|.|.:|||||||.|
Mosquito     5 CELR---YFRSVYP-DQFISSGSP---------AFPGEFAHIAAIGWTQPDGTVQWKCGGSLIWE 56

  Fly   182 RFVLTAAHCTSIYEAP-----PKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIA 241
            .::||||||   |..|     |..:|||||:|.........|..:|.|:..||.:.....|.|:|
Mosquito    57 NYILTAAHC---YADPDTILSPDVIRIGDLNLFDADDDEFVQERKIVQIIRHPLHNASTVYYDLA 118

  Fly   242 LLKLEKEVELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAEL 306
            ||||:|:|..:|.|.|..||:...:|.:.....|:|.|.|.|..:|.|....|.::.|.||....
Mosquito   119 LLKLDKKVIQSEGVIPTCLWLDDSIPFSTLEVAGWGQTGFGKEKSNMLLKAELKLMTNTECAKYN 183

  Fly   307 PPLAETPSG--VLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCR 369
            ....:...|  :.:.|:||.|.::  |||.|||||||..||..:   |.....|:|:||:|..|.
Mosquito   184 NKRTQRRLGNDLADHQLCAWDEVM--DTCPGDSGGPLHYNLYYK---HTKIPFLVGVTSFGKACA 243

  Fly   370 SSYPSVYTRVSSFLDWI 386
            .|.|.||.:|:.|..||
Mosquito   244 VSQPGVYVKVAKFKQWI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	96/248 (39%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	94/246 (38%)
AgaP_AGAP011719	XP_320793.4	Tryp_SPc	19..263	CDD:238113	96/259 (37%)
		Tryp_SPc	19..260	CDD:214473	94/257 (37%)
		Tryp_SPc	318..537	CDD:304450
		Tryp_SPc	653..>762	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910