DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP012270

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_320269.4	Gene:	AgaP_AGAP012270 / 1280418	VectorBaseID:	AGAP012270	Length:	862	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	72/263 - (27%)
Similarity:	114/263 - (43%)	Gaps:	50/263 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRS 214
            |.||.:|..|.: ::...|..:||||||:|.|..:||:.||          |.:|...::.|:.|
Mosquito    46 AMPGHWPWHAVI-YQRANGAEEYKCGGSIIDEDTILTSGHC----------VTVGSRAISPEQLS 99

  Fly   215 VEAQLLR------------IEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELP 267
            :|...:|            :.||..||....:.:.:||||:||...:.:|.:|:|:.||......
Mosquito   100 IEVGRIRLHERTEYTQTHGVRQVIVHPGLNVRRFKNDIALIKLASNITMTPHVQPICLWTMDNNQ 164

  Fly   268 TTI----AFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYIL 328
            ..|    ...:|:|.|. ...::.:|...::.||....|.|.  ..|...:.:.....|..
Mosquito   165 ELIVGKNGTVLGFGLTE-QDVVSEQLKQASIGVVDTLTCLAN--DRAAFGTYLTSEMFCGG---- 222

  Fly   329 NRD---TCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSY------GVFCRSSYPSVYTRVSSFLD 384
            .||   .|.|||||.|.|.:.||       :.:.||.|:      ...|.:|..:.:..|:.:|.
Mosquito   223 GRDGVSACNGDSGGGLFLEVEGR-------WFVRGIVSFIPLRKNTALCDTSKFTAFADVAKYLK 280

  Fly   385 WIE 387
            |||
Mosquito   281 WIE 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	70/261 (27%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	69/260 (27%)
AgaP_AGAP012270	XP_320269.4	Tryp_SPc	40..284	CDD:238113	72/263 (27%)
		Tryp_SPc	42..282	CDD:214473	69/260 (27%)
		Tryp_SPc	329..>443	CDD:304450
		Tryp_SPc	614..842	CDD:304450
		Tryp_SPc	614..839	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910