DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP008994

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_319744.4	Gene:	AgaP_AGAP008994 / 1279956	VectorBaseID:	AGAP008994	Length:	250	Species:	Anopheles gambiae

Alignment Length:	254	Identity:	77/254 - (30%)
Similarity:	126/254 - (49%)	Gaps:	27/254 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVL----ARPGEYPHMAAVGFESDRGQ-VDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGD 205
            |||:    ::.||:|....|...:..|. ...||||.||:..:|:|||||...:.|....| .|:
Mosquito     4 GRVVGGKASKFGEWPWQVLVRESTWLGLFTKNKCGGVLITNEYVITAAHCQPGFLASLVAV-FGE 67

  Fly   206 LDLASE---KRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFP--- 264
            .|::|:   ||||..   .:::|..|..|....:.:|:|:|:||..:....::.|:   ..|
Mosquito    68 FDISSDLETKRSVTK---NVKRVIVHRQYDAATFENDLAILELENPIHYDVHIVPI---CMPGDE 126

  Fly   265 -ELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYIL 328
             :....:|...|:|..::...:.:.|..:.:.|:.|:.|. |:..:|.....:|.|.:||.....
Mosquito   127 ADFTGRMATVTGWGRLTYGGGVPSVLQEVQVPVIENSVCQ-EMFHMAGHNKKILPSFVCAGYANG 190

  Fly   329 NRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSY-PSVYTRVSSFLDWI 386
            .||:|:|||||||.|..|..|      |.|:|..|:|:.|.:.| |.||.|.:.:..|:
Mosquito   191 KRDSCEGDSGGPLVLQRPDGR------YELVGTVSHGIRCAAPYLPGVYMRTTFYKPWL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	77/254 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	76/252 (30%)
AgaP_AGAP008994	XP_319744.4	Tryp_SPc	5..242	CDD:214473	75/250 (30%)
AgaP_AGAP008994	XP_319744.4	Tryp_SPc	6..246	CDD:238113	75/252 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910