DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP003960

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_318412.5	Gene:	AgaP_AGAP003960 / 1278781	VectorBaseID:	AGAP003960	Length:	579	Species:	Anopheles gambiae

Alignment Length:	266	Identity:	76/266 - (28%)
Similarity:	117/266 - (43%)	Gaps:	56/266 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ARPGEYP-HMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKR 213
            ::.|::| |:|.  |.::|...:|.||||::.:..:||||||.        |:..|   |.:::|
Mosquito    45 SKEGDWPWHVAL--FHNNRRSFEYACGGSILDQNTILTAAHCL--------WLSNG---LIAKER 96

  Fly   214 ---SVEAQLLRIEQVFA----------HPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLW---- 261
               .|....||:..:.|          ||.|......:||||:||..::..|.:|:|:.||
Mosquito    97 LLVQVGRSRLRVASIHARDHEAYELIVHPKYNVNQIANDIALIKLATDITFTNFVQPICLWNRGD 161

  Fly   262 ----VFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQIC 322
                :...|.|.|.|  ||..|.  .| |:.|....|.||...:|   :....|..:..|.|.:.
Mosquito   162 DQSSIVGTLGTVIGF--GYDETD--NP-TDTLREARLPVVSAIDC---IQSNREAFATQLTSDMF 218

  Fly   323 AQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSY------GVFCRSSYPSVYTRVSS 381
            ...|......|.|||||.|..|.      :.:.| :.|:.|:      ...|.:...:|:|.|:.
Mosquito   219 CAGYRNGTSPCNGDSGGGLFFNF------NNVWY-IRGLVSFTKPRQDTTICDTKEYTVFTDVAK 276

  Fly   382 FLDWIE 387
            :|.|||
Mosquito   277 YLRWIE 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/264 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	73/263 (28%)
AgaP_AGAP003960	XP_318412.5	Tryp_SPc	39..283	CDD:238113	76/266 (29%)
		Tryp_SPc	39..281	CDD:214473	73/263 (28%)
		Tryp_SPc	331..573	CDD:214473
		Tryp_SPc	331..573	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910