DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14642 and AgaP_AGAP004741

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_318080.4	Gene:	AgaP_AGAP004741 / 1278484	VectorBaseID:	AGAP004741	Length:	315	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	76/285 - (26%)
Similarity:	126/285 - (44%)	Gaps:	59/285 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 TAVAADANDADFDGRVL---------ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAA 188
            ||:....:||....|.|         |..|::|..|::  .:..|:....||||||..::|||||
Mosquito    51 TAIPIPRHDAPRTVRELLAKVVNGQTATTGQFPWQASI--RAALGRSVTVCGGSLIEAQWVLTAA 113

  Fly   189 HCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTE 253
            ||.:.|..  ..:.:|.:.|...:.::...:     .|.||.:......:|:||::|...|..:.
Mosquito   114 HCANDYTV--FQIGLGSIHLNMARLTMSTVI-----KFVHPEFDPWKLTNDVALIRLPSPVPYSL 171

  Fly   254 YVRPVRLWVFPELPTTIAF------AMGYGATSFA-KPMTNRLTNLNLTVVPNAEC----NAELP 307
            .:.||:|.:  .||.|..:      ..|:|.||.| :.::..|....:.::.||||    .|.:
Mosquito   172 EIYPVKLPI--NLPPTDLYIGRQVTVSGFGRTSDAIQSISTILKYERMRIISNAECTNVYGAAI- 233

  Fly   308 PLAETPSGVLESQICA----QDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSY---- 364
                    :..:.:||    :.|   ::.||||||||:.:.....      .:..|||.|:
Mosquito   234 --------IRNTTLCAVGWERPY---QNVCQGDSGGPMVMQQDDS------SWVQIGIVSFVSSR 281

  Fly   365 GVFCRSSYPSVYTRVSSFLDWIELT 389
            |  |.:..||.|.|..::|.|:..|
Mosquito   282 G--CSTGDPSGYIRTVNYLSWLAKT 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/268 (26%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/267 (26%)
AgaP_AGAP004741	XP_318080.4	Tryp_SPc	70..300	CDD:214473	68/260 (26%)
AgaP_AGAP004741	XP_318080.4	Tryp_SPc	71..304	CDD:238113	69/263 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910