DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP008403

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_317049.4	Gene:	AgaP_AGAP008403 / 1277577	VectorBaseID:	AGAP008403	Length:	873	Species:	Anopheles gambiae

Alignment Length:	244	Identity:	98/244 - (40%)
Similarity:	143/244 - (58%)	Gaps:	18/244 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 RPG---EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTS-IYEAPPKWVRIGDLDLASE 211
            ||.   |:.||||||:..:.|::|:.||||||.|.:||||||||: ...|.|..||:||::|..:
Mosquito    21 RPAYLREFAHMAAVGWTGENGKIDWNCGGSLIWENYVLTAAHCTADDNNAAPDVVRLGDINLDDD 85

  Fly   212 KRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAMGY 276
            .....||.|:|.::..||.::....|.|:|||:||:.|.|.:.|.|..||...|:|.....|.|:
Mosquito    86 SDDKYAQQLKIVEIIRHPEHRFSSRYHDLALLRLERNVTLHDTVAPGCLWNDEEIPFPSMEATGW 150

  Fly   277 GATSFAKPMTNRLTNLNLTVVPNAECNAELPP----LAETPSGVLESQICAQDYILNRDTCQGDS 337
            |:|.|||  |..|..::|::||.:.|:.:...    |.:   |:.:.|:||.|  :..|||.|||
Mosquito   151 GSTGFAK--TPILLKVSLSLVPKSTCDQQYRKGDRGLRQ---GLQDYQLCAGD--IKMDTCPGDS 208

  Fly   338 GGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSYPSVYTRVSSFLDWI 386
            |||||:.|....   ::...:|.:||:|..|..|.|.||.:||.::.||
Mosquito   209 GGPLQMKLLANA---KMTPFIIAVTSFGSVCGQSTPGVYMKVSPYIPWI 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	98/244 (40%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	96/242 (40%)
AgaP_AGAP008403	XP_317049.4	Tryp_SPc	20..256	CDD:238113	98/244 (40%)
		Tryp_SPc	20..254	CDD:214473	96/242 (40%)
		Tryp_SPc	324..552	CDD:304450
		CLIP	577..617	CDD:295450
		Tryp_SPc	656..872	CDD:304450
		Tryp_SPc	656..869	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910