DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP008558

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_314667.4	Gene:	AgaP_AGAP008558 / 1275424	VectorBaseID:	AGAP008558	Length:	574	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	74/268 - (27%)
Similarity:	125/268 - (46%)	Gaps:	53/268 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVL-----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYE----APPKWV 201
            ||::     |..|::|..||:....:|..: |:|||::|::..:||||||..:.:    .....|
Mosquito    34 GRLILGGEDAISGQWPWHAAIFHRIERSFM-YQCGGAIINQNTILTAAHCVQLNQGVITVDRLSV 97

  Fly   202 RIGDLDL-ASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLW---- 261
            ::|...| |:|..:.|.|   .|::..|..|......:||||:||..::..||||:||.||
Mosquito    98 QVGRTYLYAAESHTQEHQ---AERIIVHEEYSAAQVRNDIALIKLATDIRFTEYVQPVCLWDRAR 159

  Fly   262 -VFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQD 325
             ...:|...:...:|:|.|...: :.:||....:.:|....|              |||......
Mosquito   160 TDIGQLIGRVGTVIGFGITEIGE-VADRLRVAYMPIVDTQTC--------------LESNRNLFG 209

  Fly   326 YILNRD-----------TCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSY-GVFCRSSYPSVYTR 378
            .:|.|:           .|.|||||.:...:..|       :::.||.|: |..|:|:..:.::.
Mosquito   210 RVLTRNVFCAGFRNGTTVCGGDSGGGMYFEIENR-------WYIRGIVSFSGQNCQSADFAGFSD 267

  Fly   379 VSSFLDWI 386
            |:::||||
Mosquito   268 VATYLDWI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/268 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	72/266 (27%)
AgaP_AGAP008558	XP_314667.4	Tryp_SPc	37..277	CDD:238113	72/265 (27%)
		Tryp_SPc	37..275	CDD:214473	70/263 (27%)
		Tryp_SPc	322..568	CDD:214473
		Tryp_SPc	322..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910