DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP004570

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_313874.5	Gene:	AgaP_AGAP004570 / 1274709	VectorBaseID:	AGAP004570	Length:	259	Species:	Anopheles gambiae

Alignment Length:	246	Identity:	80/246 - (32%)
Similarity:	132/246 - (53%)	Gaps:	34/246 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 RP---GEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLD--LAS 210
            ||   .:||.:|.:.::   ||  :.||.||:::.:|||||||....:.....|.:||.|  :||
Mosquito    26 RPTGVNQYPWLARLVYD---GQ--FHCGASLLTKDYVLTAAHCVRRLKRNKIRVILGDYDQFVAS 85

  Fly   211 EKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFP----ELPTTIA 271
            |..::   :..:..:..|.::.:..|..|||||||.|.||.|:.:|||.|   |    |....:.
Mosquito    86 ETPAI---MRAVTAIIRHRSFDQNSYNHDIALLKLRKPVEFTKTIRPVCL---PKERSEPAGQLG 144

  Fly   272 FAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGD 336
            ..:|:|.||....:...:.::::.::...:|.:    :....|.:..:.:||...  .:|:||||
Mosquito   145 TVVGWGRTSEGGTLPALVQHVDVPILTLDQCRS----MKYRASRITSNMLCAGKG--KQDSCQGD 203

  Fly   337 SGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            |||||.:     |.|.:  :.::||.|:||.| |:.||.|||||:.:|.|:
Mosquito   204 SGGPLLV-----RNGDK--HEIVGIVSWGVGCGRAGYPGVYTRVARYLPWL 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	80/246 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	79/244 (32%)
AgaP_AGAP004570	XP_313874.5	Tryp_SPc	21..246	CDD:214473	79/243 (33%)
AgaP_AGAP004570	XP_313874.5	Tryp_SPc	22..250	CDD:238113	80/246 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910