DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP003691

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_313476.4	Gene:	AgaP_AGAP003691 / 1274366	VectorBaseID:	AGAP003691	Length:	831	Species:	Anopheles gambiae

Alignment Length:	296	Identity:	71/296 - (23%)
Similarity:	122/296 - (41%)	Gaps:	51/296 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 CEQKYSEYVERIFPNDTAVAAD--------------ANDADFDGRVLARPGEYPHMAAVGFESDR 167
            |..|||::  |.|.:..|..:|              .|...:..|::      |..|..|  |.|
Mosquito   226 CTSKYSDF--RDFEDSMASRSDNFVQVQYSKSRLSNTNIEQYKVRIV------PKTAETG--SKR 280

  Fly   168 GQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDL--ASEKRSVEAQLLRIEQVFAHPN 230
                 .|.||||:.:||||||:|...||.....:.:|..::  ..::.|:..: ...:::..||.
Mosquito   281 -----HCYGSLIAPKFVLTAANCLRQYEVDGYTIEMGQYNVYYPVQENSIRVR-TEAKKIHYHPE 339

  Fly   231 YKKKMYYDDIALLKLEKEV-ELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPMTNRLTNLNL 294
            :......:|:|||::.|.: ...:.|.|..:|.:.:||.......||...:.:...:.|......
Mosquito   340 FDAATLANDVALLEIVKPLYTFNKTVLPACIWPWDKLPVDEYQTNGYVPFNESDDESVRTNQFFA 404

  Fly   295 TVVPNAECNAELPPLAETPSGVLESQICAQ-DYILNRDTCQGDSGGPLQLNLPGRRRGHRIHY-- 356
            |.....||..::|          :.|.||. ...|:..:|....|..:..:|....|     |
Mosquito   405 TANVYDECLDKVP----------QHQFCAGFPTALSPKSCHNSVGSAMSRSLYALGR-----YFD 454

  Fly   357 HLIGITSYGVFCRSSYPSVYTRVSSFLDWIELTVWA 392
            ::..|.|.|..|..:.|:|||:::.::.||:..|.|
Mosquito   455 YIFAINSKGENCGFNLPTVYTKIAPYVQWIDSIVHA 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	59/246 (24%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	58/245 (24%)
AgaP_AGAP003691	XP_313476.4	Tryp_SPc	80..>152	CDD:304450
		Tryp_SPc	276..484	CDD:214473	55/230 (24%)
		Tryp_SPc	281..487	CDD:304450	54/221 (24%)
		CLIP	506..554	CDD:197829
		Tryp_SPc	600..820	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910