DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CLIPB2

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	91/285 - (31%)
Similarity:	134/285 - (47%)	Gaps:	42/285 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 FPNDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSI 193
            ||..........|....|:. ....|:|..|.:.:.....|.|:.|||:||:.|::||||||  :
Mosquito    89 FPTSPECGIQVTDRIIGGQT-TELEEFPWTALIEYRKPGNQYDFHCGGALINARYILTAAHC--V 150

  Fly   194 YEAPPKW----VRIGDLDLASEKRSVEAQL------LRIEQVFAHPNY--KKKMYYDDIALLKLE 246
            ...|..|    ||:|:.||::.....:...      |.||...||..|  ....:.:||||::|.
Mosquito   151 QSLPRGWQLNGVRLGEWDLSTANDCSDGICSAGPIDLEIESFVAHAGYDAADTAHTNDIALIRLR 215

  Fly   247 KEVELTEYVRPVRL-WVFPELPT----TIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAEL 306
            ::|..:|.:||:.| ...|:...    |::||.|:|.|..|.....:| .:.|||...:.|.
Mosquito   216 QDVASSEMIRPICLPLTEPQRSRNRVGTVSFAAGWGKTESASASERKL-KVELTVQDPSRCR--- 276

  Fly   307 PPLAETPSGV----LESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVF 367
                :...|:    ..||:||.. :..:|||.|||||||.....|.       ::|||:.|:|:.
Mosquito   277 ----QIYRGINIALKASQMCAGG-LQGKDTCTGDSGGPLMAKSAGA-------WYLIGVVSFGLS 329

  Fly   368 -C-RSSYPSVYTRVSSFLDWIELTV 390
             | .:.||.|||.|..:|||||..|
Mosquito   330 KCGTAGYPGVYTNVVEYLDWIESNV 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	85/263 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	84/262 (32%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855
		Tryp_SPc	102..350	CDD:214473	84/266 (32%)
		Tryp_SPc	103..353	CDD:238113	87/268 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24258
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	3.010