DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CLIPB8

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_312743.1	Gene:	CLIPB8 / 1273740	VectorBaseID:	AGAP003057	Length:	405	Species:	Anopheles gambiae

Alignment Length:	314	Identity:	89/314 - (28%)
Similarity:	132/314 - (42%)	Gaps:	60/314 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 YSE-YV-ERIFPNDTAVAADANDAD----------FDGRVLARPGEYPHMAAVGFESDRGQVDYK 173
            |.| || |.:.|.:...:..|.|||          ..|..||...|:|.||.:.:|.|...:...
Mosquito   102 YREPYVNETMVPKNRVASRIAFDADSCGIQSYVAKIRGGQLAEIDEFPWMAMLLYERDNNALTQG 166

  Fly   174 CGGSLISERFVLTAAHCTS-----IYEAPPKWVRIGDLDLASEKRSVEAQLLR----------IE 223
            |||:|||..:|:|||||.:     ..:...|:||:.:.::.:....|....|:          .:
Mosquito   167 CGGALISRTYVITAAHCVTGKNFQQTKGRLKFVRLREYNIHTNPDCVYENDLKDCSDDMIDLVPQ 231

  Fly   224 QVFAHPNY--KKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPE-------LPTTIAFAMGYGAT 279
            .|..||.|  :......||||:::|:....|:::|.:.|   ||       .|.......|:|.|
Mosquito   232 AVIPHPEYDSESSNQQHDIALIRIEQTPPFTDFLRSICL---PEQNFESSATPGKKLSVSGWGRT 293

  Fly   280 SFAKP------MTNRLTNLNLTVVPNAECNAELPP--LAETPSGVLESQICAQDYILNRDTCQGD 336
            ...|.      ::.....|:|..|...:|:....|  .|..|     .|:||... ..:|||.||
Mosquito   294 DIFKDNLGPDVLSPIKLKLSLPYVEREKCSKTFRPWSFALGP-----GQMCAGGE-RAKDTCAGD 352

  Fly   337 SGGPLQLNLPGRRRGHRIHYHLIGITSYGV-FCR-SSYPSVYTRVSSFLDWIEL 388
            ||.||.     .....|..:::.||.|.|| .|. ...|.|||.|..:|.||::
Mosquito   353 SGSPLM-----SYDMKRAIWYITGIVSLGVRGCGVEGLPGVYTNVHHYLPWIKM 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/274 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	77/273 (28%)
CLIPB8	XP_312743.1	CLIP	41..95	CDD:288855
		Tryp_SPc	136..399	CDD:214473	77/276 (28%)
		Tryp_SPc	139..400	CDD:238113	78/274 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910