DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CLIPD8

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_312135.5	Gene:	CLIPD8 / 1273182	VectorBaseID:	AGAP002784	Length:	588	Species:	Anopheles gambiae

Alignment Length:	452	Identity:	106/452 - (23%)
Similarity:	171/452 - (37%)	Gaps:	122/452 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GLWCLSNTHTQRLPPEGRMRPLQDDSIRSPVDRDIVFPELDAGPGKPEEKMWFHITDFQFDRVEG 78
            |.:...:.|..:.|.||.:......:...|   ..:.......|.||.:|....|:    :.::.
Mosquito   183 GAFVTGSNHFSQKPTEGSVFTTHWQATTEP---SFITRTKPPKPNKPSKKPILSIS----NNIQS 240

  Fly    79 PTQPKPKP---------------RQYPPPPMPGQ----------------------PFPPPPGGF 106
             |..||||               |::|...:|.:                      ...|.|
Mosquito   241 -TVLKPKPSTLQVCLWQLISSNQRKWPGSCLPTKQSTTSTSTTTTTTTTTTTTTTTTTTPRP--- 301

  Fly   107 KKKENKQRRLCEQKYSEYVERIFPNDTAVAADANDADFDGRVLARP------------GEYPHMA 159
                ..:|.......:....|  |..|:..:....:....:.:.||            |.:|...
Mosquito   302 ----TTRRTTTTTTTTTTTPR--PTTTSSTSTIGSSKCGIQTMGRPETRIVGGKNAPFGRWPWQV 360

  Fly   160 AV------GFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQ 218
            :|      ||.|     .::|||::|::.::.||.||..........:|:|:.|.:    .|:.|
Mosquito   361 SVRRTSFFGFSS-----THRCGGAVINDNWIATAGHCVDDLLTSQIRIRVGEYDFS----HVQEQ 416

  Fly   219 LLRIEQVFA----HPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTT-------IAF 272
            |..||:..|    ||.|....|..|:||:|||:.:....::.|:.      ||.|       .|.
Mosquito   417 LPYIERGVARKVVHPKYNFFTYEFDLALVKLEQPLVFAPHISPIC------LPATDDLLIGENAT 475

  Fly   273 AMGYGATSFAKPMTNRLTNLNLTVVPNAECNA--------ELPPLAETPSGVLESQICAQDYILN 329
            ..|:|..|....:.:.|..:::.:|.|..|.:        |..|         :..:||......
Mosquito   476 VTGWGRLSEGGTLPSVLQEVSVPIVSNDRCKSMFLRAGRHEFIP---------DIFLCAGHETGG 531

  Fly   330 RDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIELTV 390
            :|:||||||||||:      :|...||.|.||.|:|:.| .::.|.|.||:|.|:.||..||
Mosquito   532 QDSCQGDSGGPLQV------KGKDGHYFLAGIISWGIGCAEANLPGVCTRISKFVPWIMETV 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/278 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	77/277 (28%)
CLIPD8	XP_312135.5	Tryp_SPc	344..583	CDD:214473	75/268 (28%)
CLIPD8	XP_312135.5	Tryp_SPc	345..586	CDD:238113	77/270 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910