DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP003748

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_310280.7	Gene:	AgaP_AGAP003748 / 1271480	VectorBaseID:	AGAP003748	Length:	547	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	101/282 - (35%)
Similarity:	148/282 - (52%)	Gaps:	22/282 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 EQKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDR----GQVDYKCGGSL 178
            |..|.....|.:..|  |::......|.|| .|...|:|||||:|: :|:    ..|.|||||||
Mosquito    31 EGYYDHCPSRFYSED--VSSALGFFIFGGR-RAFLKEFPHMAAIGW-TDKTVSPPVVQYKCGGSL 91

  Fly   179 ISERFVLTAAHC-------TSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMY 236
            |:.::|||||||       ..|...||..||:||.:||:.:....||..:|.....|..:||...
Mosquito    92 IAAKYVLTAAHCKVDDEKYVFIRVIPPDTVRLGDTNLATTEDDETAQQFKIVSFAVHEKFKKNRK 156

  Fly   237 YDDIALLKLEKEVELTEYVRPVRLWVFPELP--TTIAFAMGYGATSFAKPMTNRLTNLNLTVVPN 299
            |.||||::|::|.:....|.|:.||....:.  ::...|:|:|.|::...|:..|..::|....:
Mosquito   157 YYDIALIELDREAKFNTAVCPICLWPLDNIHEYSSSLRAIGFGFTTYTSGMSPTLQKVSLNYYDS 221

  Fly   300 AECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSY 364
            ..||.|||..|....|:...|.|.:  ..::|.|.||||||||::|....|  .|.| |.|:.|:
Mosquito   222 DSCNNELPKDARLRYGLTSDQFCTK--TPHKDACLGDSGGPLQIDLSDVTR--TIPY-LTGVVSF 281

  Fly   365 GVFCRSSYPSVYTRVSSFLDWI 386
            |..|......|||:|:|:::||
Mosquito   282 GTGCWDGSMGVYTKVASYINWI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	95/254 (37%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	93/252 (37%)
AgaP_AGAP003748	XP_310280.7	Tryp_SPc	54..305	CDD:238113	96/257 (37%)
		Tryp_SPc	54..303	CDD:214473	94/255 (37%)
		Trypsin	316..521	CDD:278516
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910