DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	252	Identity:	86/252 - (34%)
Similarity:	127/252 - (50%)	Gaps:	40/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPK-WVRIGDLDLAS------- 210
            :||.||.:    ...::.:.|||:||::|:|||||||  ..|...| .||:|:.||.|
Mosquito   395 QYPWMALL----QDTELAFVCGGTLINKRYVLTAAHC--FREKLSKISVRLGEFDLKSDIDCDKR 453

  Fly   211 -EKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTT--IAF 272
             |:.::..|.:.:|:...|.:|..:...:||||::|..|....|.|.|:.|.|.||:.|.  |.:
Mosquito   454 GERCALPPQDIAVERTIKHKDYSARHKVNDIALIRLASEASYNENVMPICLPVSPEMRTVKEIYY 518

  Fly   273 AMGYGATSFAKPMTNRLTNLNLTV-----VPNAECNAELPPLAETPSGVLESQICAQDYILNR-D 331
            ..|:|.|.      |..::..|.|     :||..|. :|....:....|...|:||..  .|| |
Mosquito   519 VSGWGLTE------NDTSSDVLQVGLLRQLPNDVCQ-QLLQRKDKYVTVNSDQMCAIG--ANRTD 574

  Fly   332 TCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGV-FC-RSSYPSVYTRVSSFLDWI 386
            .|.|||||||:......|   .:.|   |:.|||: .| :.:.|.|||||.:::|||
Mosquito   575 NCSGDSGGPLKTVAVNAR---FVQY---GVVSYGLRTCGKETAPGVYTRVENYIDWI 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	86/252 (34%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	84/250 (34%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	84/250 (34%)
		Tryp_SPc	385..625	CDD:238113	84/250 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910