DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CLIPB4

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_307755.1	Gene:	CLIPB4 / 1269159	VectorBaseID:	AGAP003250	Length:	360	Species:	Anopheles gambiae

Alignment Length:	258	Identity:	85/258 - (32%)
Similarity:	137/258 - (53%)	Gaps:	35/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC-TSIYEAPPKW----VRIGDLDLAS--- 210
            |:|..|.:.:|...|:..:.||||:|:||::|||||| |||   |..|    ||:|:.||:|
Mosquito   118 EFPWTALIEYEKPNGRFGFHCGGSVINERYILTAAHCITSI---PRGWKVHRVRLGEWDLSSTTD 179

  Fly   211 --EKRSVEAQL-LRIEQVFAHPNY--KKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPT-- 268
              :....:|.: |.||::..||.|  :.|.:::||||::..:|:..:..:..:.|.:...|..
Mosquito   180 QEDDFYADAPIDLDIEKIIVHPGYNLQDKSHHNDIALIRFNREINYSSTISAICLPLSNSLRNRK 244

  Fly   269 ---TIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNR 330
               ..::|.|:|.|..|.....:| .:.||||...:|:   |........:..:|:||.. |..:
Mosquito   245 HAGLSSYAAGWGKTETASASQKKL-KVELTVVDVKDCS---PAYQRNGISLDSTQMCAGG-IRGK 304

  Fly   331 DTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYG-VFCRS-SYPSVYTRVSSFLDWIELTVW 391
            |||.|||||||...:.|       .::|||:.|:| ..|.: ..|.|||.|:.::|||:..::
Mosquito   305 DTCSGDSGGPLMRQMSG-------SWYLIGVVSFGPQKCGAPGVPGVYTNVAEYVDWIKDNIY 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	84/252 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	83/251 (33%)
CLIPB4	XP_307755.1	CLIP	31..83	CDD:371857
CLIPB4	XP_307755.1	Tryp_SPc	108..358	CDD:238113	85/254 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910