DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and f7

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	320	Identity:	89/320 - (27%)
Similarity:	136/320 - (42%)	Gaps:	76/320 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 ENKQRRLCEQKYSEYVE---------RIFP------NDTAVAADANDADFDGRVLARPGEYPHMA 159
            |...||.|......|::         .:||      .....||| :..|...|::.
Zfish   144 EQDGRRNCSCADGYYLDNGGQKCRSHEVFPCGKVPLLQAGKAAD-HQVDLRSRIVG--------- 198

  Fly   160 AVGFESDRGQVDYK----------CGGSLISERFVLTAAHCTSIYEAPPKWVRI--GDLDLASEK 212
              |.|..:|...::          |||.:....::||||||  :.:...|::||  |:.||..::
Zfish   199 --GSECPKGHCPWQVLLKYGEKGFCGGVIYKPTWILTAAHC--LEKLKVKFLRIVAGEHDLEVDE 259

  Fly   213 RSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPV----------RLWVFPELP 267
            .:  .||::::|:|.||.|..:....|||||:|...:..:.|..||          .||...:
Zfish   260 GT--EQLIQVDQMFTHPAYVSETADSDIALLRLRTPIVYSVYAVPVCLPLREMAERELWAVSK-- 320

  Fly   268 TTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNR-D 331
            .|::   |:|..|...|.:..|..|.:..:...||       .:..:..|.|.:....||..| |
Zfish   321 HTVS---GWGKRSEDGPTSRLLRRLLVPRIRTQEC-------VQVSNLTLTSNMFCAGYIEGRQD 375

  Fly   332 TCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCR--SSYPSVYTRVSSFLDWIELT 389
            :|:|||||||...       :|....|:||.|:|..|.  .|| .:|||||::|.||..|
Zfish   376 SCKGDSGGPLVTR-------YRDTAFLLGIVSWGKGCARPGSY-GIYTRVSNYLQWIRQT 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	76/265 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	75/264 (28%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342	5/21 (24%)
		Tryp_SPc	195..424	CDD:214473	75/263 (29%)
		Tryp_SPc	196..427	CDD:238113	76/265 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910