DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP013089

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_003436251.1	Gene:	AgaP_AGAP013089 / 11175918	VectorBaseID:	AGAP013089	Length:	634	Species:	Anopheles gambiae

Alignment Length:	258	Identity:	93/258 - (36%)
Similarity:	140/258 - (54%)	Gaps:	27/258 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVD----YKCGGSLISERFVLTAAHC--TSIYEAPPKWVRIG 204
            |.|.|:...:|.|||:|:.|...:::    :.|||:||:...|||.|||  |::|     :||:|
Mosquito   383 GGVDAQLNAWPWMAALGYRSTSFELNAGPRFLCGGTLITTLHVLTVAHCIQTALY-----FVRLG 442

  Fly   205 DLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWV-----FP 264
            :||:.|::.......:.|::...|..|.:|..|:||||:.|:|.|.:||.|||:.|.|     ..
Mosquito   443 ELDITSDQDGANPVDIYIQRWVVHERYDEKKIYNDIALVLLQKSVTITEAVRPICLPVEAKQRTK 507

  Fly   265 ELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAEC--NAELPPLAETPSGVLESQI-CAQDY 326
            :|.....|..|:||..:..|...||....:.|:|..:|  |.:|    ..|..:.:..: ||...
Mosquito   508 DLTYYAPFIAGWGAVGYNGPTAARLQEAQVVVLPVDQCAFNYKL----YFPGQIFDDTVLCAGFP 568

  Fly   327 ILNRDTCQGDSGGPLQLNLPG-RRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIE 387
            ...:|:|||||||||.  ||. ...|...:|.|||:.|||..| |:.:|.||.:|:::|.|||
Mosquito   569 QGGKDSCQGDSGGPLM--LPELSSNGQYYYYTLIGLISYGYECARAGFPGVYVKVTAYLPWIE 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	91/256 (36%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	90/255 (35%)
AgaP_AGAP013089	XP_003436251.1	CLIP	250..304	CDD:288855
		Tryp_SPc	380..628	CDD:214473	90/255 (35%)
		Tryp_SPc	381..631	CDD:238113	93/258 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910