DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP012946

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_003436544.1	Gene:	AgaP_AGAP012946 / 11175517	VectorBaseID:	AGAP012946	Length:	318	Species:	Anopheles gambiae

Alignment Length:	298	Identity:	99/298 - (33%)
Similarity:	149/298 - (50%)	Gaps:	29/298 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 RRLCEQKYSEYVERIFPNDTAV--AADANDADFD------------GRVLARPGEYPHMAAVGFE 164
            :||..:|..||...:....|.:  ........|:            |...|:.||:||.|.:||.
Mosquito    25 QRLATRKCLEYQNIVVNRQTLIPLTIKPKPIQFEVYNCTNVVQLIVGGEQAKYGEFPHHALLGFS 89

  Fly   165 SDRG---QVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVF 226
            .:.|   ..|::|||:|||::.:||||||.:.  ..|..||:|:.|  :|..:.:.....|..:.
Mosquito    90 KENGNQWDYDFRCGGTLISDQHILTAAHCFAY--GDPVIVRVGEYD--TELETDDEYDSDIASIR 150

  Fly   227 AHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTT--IAFAMGYGATSFAKPMTNRL 289
            .||||.....||||||:||:..:.|::::||..||...|..:|  ||...||..| :...::..:
Mosquito   151 RHPNYSNLRSYDDIALVKLKHPIVLSKHIRPACLWETEERNSTRYIATGFGYNET-YGTTLSTVM 214

  Fly   290 TNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRI 354
            ..:||...|.::|............||.:.|:|....:..|||||||||||||:....:    ..
Mosquito   215 MKVNLDEFPVSDCERNFKGDRRFKQGVRDGQLCVGSIVEGRDTCQGDSGGPLQVVTNTK----SC 275

  Fly   355 HYHLIGITSYGVFCR-SSYPSVYTRVSSFLDWIELTVW 391
            .|.::||||.|..|. .:..::||:||.::||||..||
Mosquito   276 SYGVVGITSVGGVCGIGNAKAIYTKVSHYIDWIEDNVW 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	88/246 (36%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	87/245 (36%)
AgaP_AGAP012946	XP_003436544.1	Tryp_SPc	69..311	CDD:238113	90/250 (36%)
AgaP_AGAP012946	XP_003436544.1	Tryp_SPc	69..308	CDD:214473	87/247 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BNNF
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.810