DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and F11

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	302	Identity:	89/302 - (29%)
Similarity:	125/302 - (41%)	Gaps:	50/302 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 ENKQRRLCEQKYSE----------------YVERIFPNDTAVAADANDADFDGRVLARPGEYPHM 158
            |..:|..|..|.|.                |..|:...|.......|.....|..... ||:|..
Mouse   341 ERNRRGRCYLKLSSNGSPTRILHGRGGISGYSLRLCKMDNVCTTKINPRVVGGAASVH-GEWPWQ 404

  Fly   159 AAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIE 223
              |.....:|.:   ||||:|..:::||||||.|..|.|.|....|.:...||.....| ..|::
Mouse   405 --VTLHISQGHL---CGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVNQSEINEGTA-FFRVQ 463

  Fly   224 QVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPT--------TIAFAMGYGATS 280
            ::..|..|.......||||||||..:..|::.||:.      ||:        |..:..|:|.|:
Mouse   464 EMIIHDQYTTAESGYDIALLKLESAMNYTDFQRPIC------LPSKGDRNAVHTECWVTGWGYTA 522

  Fly   281 FAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNL 345
            ....:.:.|....:.:|.|.||....     ....:....|||......:|||:|||||||....
Mouse   523 LRGEVQSTLQKAKVPLVSNEECQTRY-----RRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKY 582

  Fly   346 PGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            .|       .:||:||||:|..| :...|.|||.|:.::|||
Mouse   583 NG-------VWHLVGITSWGEGCGQKERPGVYTNVAKYVDWI 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	80/250 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	78/248 (31%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519	7/34 (21%)
		Tryp_SPc	389..617	CDD:214473	78/252 (31%)
		Tryp_SPc	390..617	CDD:238113	78/251 (31%)
		Heparin-binding. /evidence=ECO:0000250	547..550		0/7 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910