DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	258	Identity:	76/258 - (29%)
Similarity:	112/258 - (43%)	Gaps:	65/258 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 YPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC-----TSIYEAPPKWVRIG-----DLDLA 209
            :|..|::.:.|  ||.   ||||||::.:||:||||     ...|..    |.:|     ..|.:
Zfish   319 WPWQASLYWYS--GQT---CGGSLINKEWVLSAAHCFNGQRNGFYLT----VILGPKTQNKYDPS 374

  Fly   210 SEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL-------------W 261
            ...|||:|       |..||.|......:||||::|...:..|:.:|||.|             |
Zfish   375 RISRSVKA-------VIKHPYYNPNTNDNDIALVRLSFPITFTDSIRPVCLAAEGSVFNSDTESW 432

  Fly   262 VFPELPTTIAFAMGYGATSFAKPMTNR--LTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQ 324
            :     ||      :...|...|:.:.  ...:.:.|:.|.:||.     ......:.::.|||.
Zfish   433 I-----TT------WRNISDGVPLPSPKIFQEVEVPVIGNRQCNC-----LYGVGSITDNMICAG 481

  Fly   325 DYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            .....:|.||||||||:..|       ....:...||.|:|..| :|.:|.||||||.:.:||
Zfish   482 LLKEGKDLCQGDSGGPMVSN-------QSSVWVQSGIVSFGSGCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	76/258 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	74/256 (29%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035
		Tryp_SPc	309..537	CDD:238113	74/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910