DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	79/290 - (27%)
Similarity:	123/290 - (42%)	Gaps:	65/290 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 NDTAVAADAN-----------DADFDGRVL----ARPGEYPHMAAVGFESDRGQVD--------- 171
            |.:|..|..|           ....|.|::    |..|::|           .||:
Frog   237 NYSATCASGNMVSLRCISCGLSTKVDSRIVGGTPASVGDWP-----------WQVELLKLVGTSI 290

  Fly   172 YKCGGSLISERFVLTAAHCTSIYEAPPKWVRI--GDLDLASEKRSVEAQLLRIEQVFAHPNYKKK 234
            |.||||:|:..:::|||||.....:.|...::  |.|.:    :|..:....:|:...||:|...
Frog   291 YLCGGSIITPHWIVTAAHCVYGSTSTPSAFKVFAGSLTI----QSYYSAGYTVERALVHPSYSSY 351

  Fly   235 MYYDDIALLKLEKEVELTEYVRPVRL------WVFPELPTTIAFAMGYGATSFAKPMTNRLTNLN 293
            ....|:|||||...:..|..:|||.|      |...: |..|:   |:|.|:....::..|...:
Frog   352 TQIYDVALLKLTAALVFTTNLRPVCLPNVGMPWAEGQ-PCWIS---GWGTTAEGGSISKNLMAAS 412

  Fly   294 LTVVPNAECNAELPPLAETPSGVLESQICAQDYIL-NRDTCQGDSGGPLQLNLPGRRRGHRIHYH 357
            :.::.:..||.     |....|.:.|.:....|:. ..|||||||||||.......       :.
Frog   413 VPIISSTTCNQ-----AAVYGGAISSTMMCAGYLSGGTDTCQGDSGGPLVTKTNSL-------WW 465

  Fly   358 LIGITSYGVFCRSSY-PSVYTRVSSFLDWI 386
            |:|.||:|..|..:| |.||..|:.|::||
Frog   466 LVGDTSWGYGCARAYKPGVYGNVTVFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/264 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	72/262 (27%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	4/21 (19%)
		Tryp_SPc	265..498	CDD:238113	73/262 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910