DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14642 and hgf

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_002933142.2	Gene:	hgf / 100495840	XenbaseID:	XB-GENE-999992	Length:	710	Species:	Xenopus tropicalis

Alignment Length:	241	Identity:	72/241 - (29%)
Similarity:	102/241 - (42%)	Gaps:	52/241 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 SDRGQVDYKCGGSLISERFVLTAAHC-------TSIYEAPPKWVRIGDLDLASEKRSVEAQLLRI 222
            |.|.:..:||||:||.|.:||||..|       ...|||   |:.:.::...:||..   |:|.|
Frog   493 SVRYRNSHKCGGTLIKENWVLTARQCFLSGDNDLKDYEA---WLGVHNIYSTTEKHK---QVLNI 551

  Fly   223 EQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL----WVFPELPTTIAFAMGYGATSFAK 283
            .|:...|.      ..::.||||.:...|..||..::|    ...||  .|:....|:|.|.
Frog   552 SQLVHGPK------GSNLVLLKLSRPATLNAYVDRIKLPNYGCTIPE--NTMCSVYGWGHTG--- 605

  Fly   284 PMTN----RLTNLNLTVVPNAECNAELPPLAETPSG---VLESQICAQDYILNRDTCQGDSGGPL 341
              ||    :|....|.:|.|.:||       |...|   |.||:|||.....|...|:.|.||||
Frog   606 --TNDYDGQLQEGTLHIVGNEKCN-------EHHKGKITVNESEICAMSETANIGPCERDYGGPL 661

  Fly   342 QLNLPGRRRGHRIHYHLIGITSYGVFCR-SSYPSVYTRVSSFLDWI 386
               :....|.|.:.    |:...|..|. ...|.::.||:.:..||
Frog   662 ---ICEENRTHLVQ----GVIIPGRGCAIQKRPVIFVRVAYYAKWI 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/241 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/239 (29%)
hgf	XP_002933142.2	PAN_AP_HGF	26..109	CDD:238532
		KR	113..195	CDD:214527
		KR	197..275	CDD:214527
		Kringle	289..367	CDD:333799
		KR	373..454	CDD:238056
		Tryp_SPc	478..703	CDD:238113	72/241 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910