DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and prss12

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_002934300.3	Gene:	prss12 / 100495119	XenbaseID:	XB-GENE-984837	Length:	851	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	82/251 - (32%)
Similarity:	118/251 - (47%)	Gaps:	36/251 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 GEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIY--EAPPKWVRIGDL-DLASEKRS 214
            |.:|...|:..:|..|.....||.:|||..:|||||||...|  ......:|:||. .|..|:..
Frog   616 GGWPWQVALRLKSSHGDGRLLCGATLISSCWVLTAAHCFKRYGNNTRSYVIRVGDYHTLVPEEYE 680

  Fly   215 VEAQLLRIEQVFAHPNYKKKMYYDDIALLKL----EKEVELTEYVRPVRLWVFPELPTTIA---F 272
            .:   :.|:|:..|.:|:......||||::|    |:.|:|:.:|.|..|.:..|.|...|   :
Frog   681 ED---MTIQQIIIHNDYRPDGNDYDIALIRLHGTAEQCVQLSTHVLPACLPLRRERPQKTASNCY 742

  Fly   273 AMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICA-----QDYILNRDT 332
            ..|:|.|..|...|  |....:|::|...|....      .|......:||     |.::   |:
Frog   743 ITGWGDTGRAYSRT--LQQATVTLLPKRVCEERY------RSQFTGRMLCAGSVKTQKHV---DS 796

  Fly   333 CQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCR-SSYPSVYTRVSSFLDWIE 387
            |||||||||.....|   |..|.|   |:||:|..|. ...|.|||:||:|:.||:
Frog   797 CQGDSGGPLVCERSG---GSWIVY---GVTSWGYGCGVKDSPGVYTKVSAFIPWIK 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	81/249 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	80/248 (32%)
prss12	XP_002934300.3	KR	78..140	CDD:412161
		SRCR	148..244	CDD:395421
		SR	257..356	CDD:214555
		SR	363..461	CDD:214555
		SR	476..575	CDD:214555
		Tryp_SPc	607..848	CDD:238113	82/251 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910