DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and f12

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	379	Identity:	98/379 - (25%)
Similarity:	155/379 - (40%)	Gaps:	91/379 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PELDAGPG----KPEEKMWFHITDFQFDRVEGPTQPKPKPRQYPPP----------PMPGQPFPP 101
            |:.|..|.    |.:...|.|....:..::.|.|.| ||..:.|.|          |.|......
Frog   270 PDGDTQPWCFVMKEQRLSWEHCLIPRCTQLAGTTAP-PKVTKTPSPTKSSNHSASTPSPSNDTQG 333

  Fly   102 PPGGFKKKENKQRRL-----CEQKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEYPHMAAV 161
            |..|         |:     |.:|:.: ...|.|.            ..|.::|.|..:|::||:
Frog   334 PVDG---------RIDLPVDCGRKFQK-TPSIMPR------------IVGGLVALPASHPYIAAL 376

  Fly   162 GFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQ---LLRIE 223
            ..:      ::.|||||||..:::|||||   .:..|...:| .:.|...:.:...|   .|.:|
Frog   377 YID------NHFCGGSLISPCWIVTAAHC---LDQRPNVTKI-SVVLGQSRFNTTDQHTVTLLVE 431

  Fly   224 QVFAHPNYKKKMYYDDIALLKLEK-----EVELTEYVRPVRL-WVFPELPTT---IAFAMGY--- 276
            :...|..|.......||||:|::.     ..|.:::|:|:.| ..|....:|   :....|:
Frog   432 KYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKMAESTKQCVVAGWGHQYE 496

  Fly   277 GATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPS----GVLESQICAQDYILNRDTCQGDS 337
            ||..:|    ..|...::.::|..:|        ::||    .:|...:||.......|.|||||
Frog   497 GAEHYA----FFLQEASMPIIPYTQC--------QSPSVHGDRMLPGMLCAGFMEGGVDACQGDS 549

  Fly   338 GGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIELTV 390
            ||||...:.|     ||..|  |:.|:|..| ..:.|.|||.|:|:.|||...:
Frog   550 GGPLVCEVDG-----RIELH--GVVSWGSGCAEENKPGVYTAVTSYTDWIRANI 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	75/260 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	74/259 (29%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527	6/27 (22%)
		Tryp_SPc	359..595	CDD:238113	76/264 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910