DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and corin

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_004911266.2	Gene:	corin / 100492163	XenbaseID:	XB-GENE-950958	Length:	1123	Species:	Xenopus tropicalis

Alignment Length:	254	Identity:	77/254 - (30%)
Similarity:	122/254 - (48%)	Gaps:	31/254 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESD-RGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKW---VRIGDL 206
            ||. :|||.:|...::  :|| .|.:   ||..||.:::|||.|||....|:...|   ..|.:|
Frog   886 GRT-SRPGRWPWQCSL--QSDPSGHI---CGCVLIGKKWVLTVAHCFEGRESAAVWKVVFGINNL 944

  Fly   207 DLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPEL--PTT 269
            |..|:    .||...::::..||.|.:.:...||::::|.:::..|.|||||.|....:|  |.|
Frog   945 DHPSD----FAQTRLVKKIILHPRYNRAVVDYDISIVELNEDITETSYVRPVCLPTKGQLVEPDT 1005

  Fly   270 IAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQ 334
            ..:..|:|  .....|..:|....:.::....|.:..     ....:....:||.......|:|.
Frog  1006 YCYITGWG--HMGNKMPFKLQEGEVRIISLERCQSYF-----DMKTITSRMLCAGYESGTIDSCM 1063

  Fly   335 GDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSY--PSVYTRVSSFLDWIELTVW 391
            |||||||....||.:      :.|.|:||:|..|.|..  |.||:.||.|::|||..::
Frog  1064 GDSGGPLVCEKPGGK------WTLYGLTSWGSVCFSKVLGPGVYSNVSHFVEWIERQIY 1116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	75/248 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	74/247 (30%)
corin	XP_004911266.2	CRD_corin_1	213..341	CDD:143554
		LDLa	351..382	CDD:238060
		LDLa	384..418	CDD:238060
		LDLa	420..455	CDD:238060
		LDLa	465..492	CDD:238060
		CRD_corin_2	533..654	CDD:143579
		LDLa	659..693	CDD:238060
		LDLa	734..768	CDD:238060
		Tryp_SPc	883..1114	CDD:238113	77/250 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910