DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14642 and tmprss3

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	80/248 - (32%)
Similarity:	126/248 - (50%)	Gaps:	39/248 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 GEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYE-APPKW--VRIGDLDLASEKRS 214
            |::|..|::.|     |..:.||||||:.::::|||||  :|: ..|:|  |::|.:..|||...
Frog   253 GQWPWQASLVF-----QGVHLCGGSLITPQWIVTAAHC--VYDLLYPEWWRVQVGQVSQASESAQ 310

  Fly   215 VEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL----WVFPELPTTIAFAMG 275
            .   .:.::::..|..|:.....:||||::|.........::|:.|    ..|||  ..|.:..|
Frog   311 T---AVPVQKIIYHSKYRSSTMANDIALIRLASPFTFNGSIQPICLPNYREDFPE--GKICWISG 370

  Fly   276 YGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLE-SQICAQDYILNRDTCQGDSGG 339
            :|||......:..:....:.::.|..||.:.     ...||:: |.:||.......|||||||||
Frog   371 WGATEEGGDTSQTMDYAGVPLISNRVCNTKY-----IYGGVIKPSMVCAGFLEGGVDTCQGDSGG 430

  Fly   340 PL---QLNLPGRRRGHRIHYHLIGITSYGVFCRSSY-PSVYTRVSSFLDWIEL 388
            ||   ..|:          :.|:|.||:|:.|...| |.||||:|||||||.:
Frog   431 PLACEDSNV----------WKLMGTTSWGIGCALRYKPGVYTRISSFLDWIHI 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	79/245 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	78/244 (32%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055
		Tryp_SPc	244..472	CDD:238113	79/245 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910