DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and tmprss15

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	75/285 - (26%)
Similarity:	138/285 - (48%)	Gaps:	50/285 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 CEQKYSEYVERIFP-NDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLIS 180
            |:|:  |..:|:.| ...:.....:||..        |.:|.:.:: :.:||    ..||.||::
Frog   742 CQQR--ECGKRLVPIKSGSKIVGGSDAAL--------GAWPWIVSL-YYNDR----QTCGASLVN 791

  Fly   181 ERFVLTAAHCTSIYE---APPKW-VRIG---DLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYD 238
            :.::::||||  :|.   .|..| .|:|   :|:|...:  :..|:  |:|:..:|.|.::....
Frog   792 QEWLVSAAHC--VYGRNLIPSNWKARLGLHTNLNLTQPQ--IATQM--IDQIVINPQYNRRTKDS 850

  Fly   239 DIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAM-----GYGATSFAKPMTNRLTNLNLTVVP 298
            ||.::.|:.:|..::|::|:.|   ||.....:..:     |:|.|....|:.|.|....:.::.
Frog   851 DIVMMHLQFKVNYSDYIQPICL---PETDQEFSVGINCSIAGWGRTQSGGPVPNILQEAEIPLIS 912

  Fly   299 NAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITS 363
            |.:|..::|..     .:.::.:|........||||||||||:...       ....:.|:|:||
Frog   913 NHKCQQQMPEY-----NITDNMVCGGYEEGGIDTCQGDSGGPMMCQ-------QNNEWFLVGVTS 965

  Fly   364 YGVFC-RSSYPSVYTRVSSFLDWIE 387
            :|..| :.|.|.||.||:.|.:||:
Frog   966 FGYGCAQPSRPGVYVRVTEFTNWIK 990

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	67/253 (26%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	66/252 (26%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504
		CUB	501..608	CDD:395345
		LDLa	620..654	CDD:238060
		SR	655..746	CDD:214555	2/5 (40%)
		Tryp_SPc	760..991	CDD:238113	70/265 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910