DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14642 and klkb1

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	82/286 - (28%)
Similarity:	125/286 - (43%)	Gaps:	47/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 RLCEQKY-------SEYVERIFPNDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDY 172
            |||:.|.       .|:..||.....:|.                ||:|...::..........:
Frog   371 RLCKIKSVKGCGEPIEHANRIVGGTDSVL----------------GEWPWQVSMHLRLTASYKKH 419

  Fly   173 KCGGSLISERFVLTAAHCTSIYEAPPKW-VRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMY 236
            .||||:||.::::|||||.:::..|..| :..|.:.|::..:|  ......||:..||:|.....
Frog   420 ACGGSIISNQWIVTAAHCFAMHPLPQMWIIYSGVVKLSNITQS--TPFSETEQIIIHPHYTGAGN 482

  Fly   237 YDDIALLKLEKEVELTEYVRPVRLWVFPELPTTI----AFAMGYGATSFAKPMTNRLTNLNLTVV 297
            ..|||||||:..:...::.:.:.|  .|..||.:    .:..|:|.|..:..:.|.|....:..:
Frog   483 GTDIALLKLKTPISFNDHQKAICL--PPREPTFVLPNSCWITGWGFTEESGSLANILQKAEVPQI 545

  Fly   298 PNAECNAELPPLAETPSGVLESQICAQDYILNR-DTCQGDSGGPLQLNLPGRRRGHRIHYHLIGI 361
            ...||........      ::.:|....|...: |:|:|||||||...:      ..|.| |.||
Frog   546 STEECQGNYEQTR------IDKKILCAGYKRGKIDSCKGDSGGPLACVV------DEIWY-LTGI 597

  Fly   362 TSYGVFC-RSSYPSVYTRVSSFLDWI 386
            ||:|..| |...|.||||||.|.|||
Frog   598 TSWGEGCARPGKPGVYTRVSEFTDWI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	74/248 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	72/246 (29%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519	1/1 (100%)
		Tryp_SPc	391..626	CDD:238113	76/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910