DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and tmprss11f

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_004911133.1	Gene:	tmprss11f / 100379970	XenbaseID:	XB-GENE-1012399	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	75/270 - (27%)
Similarity:	125/270 - (46%)	Gaps:	41/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 TAVAADANDADFDG-----RVL----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAA 188
            |..|||.......|     |::    |..|.:|..|::     |....:.||.||:::.:::.||
Frog   177 TTTAADFTACGIGGPSVSNRIVGGTNAGLGSWPWQASL-----RLLGSHTCGASLLNDTWLVAAA 236

  Fly   189 HCTSIYEAPPKW-VRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELT 252
            ||..:......| |.:|.:::.|...      .:||::..:..|....:.:|||||||...:..|
Frog   237 HCFDMNADANSWTVVLGTINVYSGSE------FKIEKIIIYEGYTSHNHRNDIALLKLFTPLNFT 295

  Fly   253 EYVRPVRL----WVFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETP 313
            ..:|||.|    .:||:  .:..:..|:||.:.....:..|....:.::.:..|::     ::..
Frog   296 SIIRPVCLPEASDIFPD--GSSCYITGWGALTDGGSASQVLQQAEVKIINSDTCSS-----SQMY 353

  Fly   314 SGVL-ESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCR-SSYPSVY 376
            .|:: .|.|||.......|:|||||||||.....||       :.||||.|:|..|. .:.|.||
Frog   354 GGLIYPSMICAGYATGQIDSCQGDSGGPLVTLKSGR-------WVLIGIVSFGYGCALPNKPGVY 411

  Fly   377 TRVSSFLDWI 386
            :|::...:||
Frog   412 SRITYLRNWI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/257 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	69/255 (27%)
tmprss11f	XP_004911133.1	SEA	48..148	CDD:396113
tmprss11f	XP_004911133.1	Tryp_SPc	197..421	CDD:238113	67/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000